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alpha-(bromomethyl)benzyl alcohol

  • CAS:2425-28-7
  • purity:99%
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alpha-(bromomethyl)benzyl alcohol 2425-28-7 with purity >99% Low price in stock

  • Molecular Formula: C8H9 Br O
  • Molecular Weight: 201.063
  • Vapor Pressure: 0.00578mmHg at 25°C 
  • Melting Point: 39°C 
  • Refractive Index: 1.5800 (estimate) 
  • Boiling Point: 261.6°Cat760mmHg 
  • PKA: 13.00±0.20(Predicted) 
  • Flash Point: 135.6°C 
  • PSA: 20.23000 
  • Density: 1.503g/cm3 
  • LogP: 2.11490 

alpha-(bromomethyl)benzyl alcohol(Cas 2425-28-7) Usage

General Description

Alpha-(bromomethyl)benzyl alcohol is a chemical compound with the molecular formula C8H9BrO. It is an organic compound that contains a benzyl group substituted with a bromomethyl group and a hydroxyl group at the alpha position. alpha-(bromomethyl)benzyl alcohol is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also used as a reagent in organic synthesis, particularly in the formation of carbon-carbon and carbon-oxygen bonds. Alpha-(bromomethyl)benzyl alcohol is considered to be a hazardous chemical and should be handled with care due to its potential to cause skin and eye irritation and its toxic effects if ingested or inhaled.

InChI:InChI=1/C8H9BrO/c9-6-8(10)7-4-2-1-3-5-7/h1-5,8,10H,6H2/t8-/m1/s1

2425-28-7 Relevant articles

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Buckles,Maurer

, p. 1585,1587 (1953)

-

An 18O-Labeling Study of the β-(Nitroxy)alkyl and β-(Trifluoroacetoxy)alkyl Radical Migrations: Further Examples of a 1,2-Shift Mechanism

Crich, David,Filzen, G. Frederick

, p. 4834 - 4837 (1995)

The results of an 18O labeling study of ...

Metalated Ir–CNP Complexes Containing Imidazolin-2-ylidene and Imidazolidin-2-ylidene Donors – Synthesis, Structure, Luminescence, and Metal–Ligand Cooperative Reactivity

Hernández-Juárez, Martín,Sánchez, Práxedes,López-Serrano, Joaquín,Lara, Patricia,González-Herrero, Pablo,Rendón, Nuria,álvarez, Eleuterio,Paneque, Margarita,Suárez, Andrés

, p. 3944 - 3953 (2020)

The iridium complex 1 based on a metalat...

A vanadium-dependent bromoperoxidase in the marine red alga Kappaphycus alvarezii (Doty) Doty displays clear substrate specificity

Kamenarska, Zornitsa,Taniguchi, Tomokazu,Ohsawa, Noboru,Hiraoka, Masanori,Itoh, Nobuya

, p. 1358 - 1366 (2007)

Bromoperoxidase activity was initially d...

In situ NMR study of asymmetric borane reduction reaction - An abnormal factor in the temperature effect on the bis-oxazaborolidine catalyst and the relationship between the catalyst structure and selectivity

Zhao, Jinkai,Bao, Xinhe,Liu, Xiumei,Wan, Boshun,Han, Xiuwen,Yang, Caiguang,Hang, Jiangfeng,Feng, Yan,Jiang, Biao

, p. 3351 - 3359 (2000)

The relationship between the structure o...

A highly regio- and chemoselective synthesis of vicinal bromohydrins by ring opening of terminal epoxides with dibromoborane-dimethyl sulfide

Roy, Chandra D.,Brown, Herbert C.

, p. 1608 - 1613 (2007)

Dibromoborane-dimethyl sulfide (BHBr2-SM...

New chiral borohydride based reducing agent: Asymmetric reduction of 9-anthryl trifluoromethyl ketone and other carbonyl compounds

Maiti, Dilip K.,Bhattacharya, Pranab K.

, p. 99 - 108 (1998)

(S)-(+)-2-(α-Hydroxybenzyl)benzimidazole...

Asymmetric hydrolysis of (dl)-1-acyloxy-2-halo-1-phenylethanes with lipases

Kutsuki,Sawa,Hasegawa,Watanabe

, p. 2369 - 2373 (1986)

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Enantioselective borane reduction of aromatic ketones catalyzed by chiral aluminum alkoxides

Fu, I.-Pin,Uang, Biing-Jiun

, p. 45 - 48 (2001)

The asymmetric borane reduction of proch...

Regio- and stereoselective synthesis of bromoalkenes by homolytic hydrobromination of alkynes with hydrogen bromide

Kumaki, Wataru,Kinoshita, Hidenori,Miura, Katsukiyo

supporting information, (2022/03/07)

Homolytic hydrobromination of terminal a...

Unmasking the Hidden Carbonyl Group Using Gold(I) Catalysts and Alcohol Dehydrogenases: Design of a Thermodynamically-Driven Cascade toward Optically Active Halohydrins

Escot, Lorena,González-Granda, Sergio,Gotor-Fernández, Vicente,Lavandera, Iván

, p. 2552 - 2560 (2022/02/16)

A concurrent cascade combining the use o...

Chiral salen - Ni (II) based spherical porous silica as platform for asymmetric transfer hydrogenation reaction and synthesis of potent drug intermediate montekulast

Shukla, Meenakshi,Barick,Salunke,Chandra, Sudeshna

, (2021/02/05)

Heterogeneous catalyst has an edge over ...

Alkene, Bromide, and ROH – How To Achieve Selectivity? Electrochemical Synthesis of Bromohydrins and Their Ethers

Bityukov, Oleg V.,Nikishin, Gennady I.,Terent'ev, Alexander O.,Vil', Vera A.

supporting information, p. 3070 - 3078 (2021/05/10)

Bromohydrins and their ethers were elect...

2425-28-7 Process route

α-bromoacetophenone
70-11-1

α-bromoacetophenone

10-methylacridinium cation
13367-81-2

10-methylacridinium cation

1-Phenylethanol
98-85-1,13323-81-4

1-Phenylethanol

2-Bromo-1-phenylethanol
2425-28-7

2-Bromo-1-phenylethanol

acetophenone
98-86-2

acetophenone

Conditions
Conditions Yield
With perchloric acid; 9,10-dihydro-10-methylacridine; In [D3]acetonitrile; at 61.9 ℃; for 11h; Title compound not separated from byproducts;
14 % Spectr.
82 % Spectr.
100 % Spectr.
4 % Spectr.
methyllithium lithium bromide

methyllithium lithium bromide

tri-n-butylstannylmethylfluoride
1620586-86-8

tri-n-butylstannylmethylfluoride

benzaldehyde
100-52-7

benzaldehyde

styrene oxide
96-09-3

styrene oxide

1-Phenylethanol
98-85-1,13323-81-4

1-Phenylethanol

2-Bromo-1-phenylethanol
2425-28-7

2-Bromo-1-phenylethanol

2-fluoro-1-phenylethanol
450-94-2

2-fluoro-1-phenylethanol

methyltributyltin
1528-01-4

methyltributyltin

Conditions
Conditions Yield
In tetrahydrofuran; at -98 ℃; Inert atmosphere;
15 %Spectr.
20 %Spectr.
55 %Spectr.

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