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alpha-(bromomethyl)benzyl alcohol 2425-28-7 with purity >99% Low price in stock
- Molecular Formula: C8H9 Br O
- Molecular Weight: 201.063
- Vapor Pressure: 0.00578mmHg at 25°C
- Melting Point: 39°C
- Refractive Index: 1.5800 (estimate)
- Boiling Point: 261.6°Cat760mmHg
- PKA: 13.00±0.20(Predicted)
- Flash Point: 135.6°C
- PSA: 20.23000
- Density: 1.503g/cm3
- LogP: 2.11490
alpha-(bromomethyl)benzyl alcohol(Cas 2425-28-7) Usage
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General Description |
Alpha-(bromomethyl)benzyl alcohol is a chemical compound with the molecular formula C8H9BrO. It is an organic compound that contains a benzyl group substituted with a bromomethyl group and a hydroxyl group at the alpha position. alpha-(bromomethyl)benzyl alcohol is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also used as a reagent in organic synthesis, particularly in the formation of carbon-carbon and carbon-oxygen bonds. Alpha-(bromomethyl)benzyl alcohol is considered to be a hazardous chemical and should be handled with care due to its potential to cause skin and eye irritation and its toxic effects if ingested or inhaled. |
InChI:InChI=1/C8H9BrO/c9-6-8(10)7-4-2-1-3-5-7/h1-5,8,10H,6H2/t8-/m1/s1
2425-28-7 Relevant articles
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Buckles,Maurer
, p. 1585,1587 (1953)
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An 18O-Labeling Study of the β-(Nitroxy)alkyl and β-(Trifluoroacetoxy)alkyl Radical Migrations: Further Examples of a 1,2-Shift Mechanism
Crich, David,Filzen, G. Frederick
, p. 4834 - 4837 (1995)
The results of an 18O labeling study of ...
Metalated Ir–CNP Complexes Containing Imidazolin-2-ylidene and Imidazolidin-2-ylidene Donors – Synthesis, Structure, Luminescence, and Metal–Ligand Cooperative Reactivity
Hernández-Juárez, Martín,Sánchez, Práxedes,López-Serrano, Joaquín,Lara, Patricia,González-Herrero, Pablo,Rendón, Nuria,álvarez, Eleuterio,Paneque, Margarita,Suárez, Andrés
, p. 3944 - 3953 (2020)
The iridium complex 1 based on a metalat...
A vanadium-dependent bromoperoxidase in the marine red alga Kappaphycus alvarezii (Doty) Doty displays clear substrate specificity
Kamenarska, Zornitsa,Taniguchi, Tomokazu,Ohsawa, Noboru,Hiraoka, Masanori,Itoh, Nobuya
, p. 1358 - 1366 (2007)
Bromoperoxidase activity was initially d...
In situ NMR study of asymmetric borane reduction reaction - An abnormal factor in the temperature effect on the bis-oxazaborolidine catalyst and the relationship between the catalyst structure and selectivity
Zhao, Jinkai,Bao, Xinhe,Liu, Xiumei,Wan, Boshun,Han, Xiuwen,Yang, Caiguang,Hang, Jiangfeng,Feng, Yan,Jiang, Biao
, p. 3351 - 3359 (2000)
The relationship between the structure o...
A highly regio- and chemoselective synthesis of vicinal bromohydrins by ring opening of terminal epoxides with dibromoborane-dimethyl sulfide
Roy, Chandra D.,Brown, Herbert C.
, p. 1608 - 1613 (2007)
Dibromoborane-dimethyl sulfide (BHBr2-SM...
New chiral borohydride based reducing agent: Asymmetric reduction of 9-anthryl trifluoromethyl ketone and other carbonyl compounds
Maiti, Dilip K.,Bhattacharya, Pranab K.
, p. 99 - 108 (1998)
(S)-(+)-2-(α-Hydroxybenzyl)benzimidazole...
Asymmetric hydrolysis of (dl)-1-acyloxy-2-halo-1-phenylethanes with lipases
Kutsuki,Sawa,Hasegawa,Watanabe
, p. 2369 - 2373 (1986)
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Enantioselective borane reduction of aromatic ketones catalyzed by chiral aluminum alkoxides
Fu, I.-Pin,Uang, Biing-Jiun
, p. 45 - 48 (2001)
The asymmetric borane reduction of proch...
Regio- and stereoselective synthesis of bromoalkenes by homolytic hydrobromination of alkynes with hydrogen bromide
Kumaki, Wataru,Kinoshita, Hidenori,Miura, Katsukiyo
supporting information, (2022/03/07)
Homolytic hydrobromination of terminal a...
Unmasking the Hidden Carbonyl Group Using Gold(I) Catalysts and Alcohol Dehydrogenases: Design of a Thermodynamically-Driven Cascade toward Optically Active Halohydrins
Escot, Lorena,González-Granda, Sergio,Gotor-Fernández, Vicente,Lavandera, Iván
, p. 2552 - 2560 (2022/02/16)
A concurrent cascade combining the use o...
Chiral salen - Ni (II) based spherical porous silica as platform for asymmetric transfer hydrogenation reaction and synthesis of potent drug intermediate montekulast
Shukla, Meenakshi,Barick,Salunke,Chandra, Sudeshna
, (2021/02/05)
Heterogeneous catalyst has an edge over ...
Alkene, Bromide, and ROH – How To Achieve Selectivity? Electrochemical Synthesis of Bromohydrins and Their Ethers
Bityukov, Oleg V.,Nikishin, Gennady I.,Terent'ev, Alexander O.,Vil', Vera A.
supporting information, p. 3070 - 3078 (2021/05/10)
Bromohydrins and their ethers were elect...
2425-28-7 Process route
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70-11-1
α-bromoacetophenone
-
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13367-81-2
10-methylacridinium cation
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-
98-85-1,13323-81-4
1-Phenylethanol
-
-
2425-28-7
2-Bromo-1-phenylethanol
-
-
98-86-2
acetophenone
| Conditions | Yield |
|---|---|
|
With
perchloric acid; 9,10-dihydro-10-methylacridine;
In
[D3]acetonitrile;
at 61.9 ℃;
for 11h;
Title compound not separated from byproducts;
|
14 % Spectr.
82 % Spectr. 100 % Spectr. 4 % Spectr. |
-
-
methyllithium lithium bromide
-
-
1620586-86-8
tri-n-butylstannylmethylfluoride
-
-
100-52-7
benzaldehyde
-
-
96-09-3
styrene oxide
-
-
98-85-1,13323-81-4
1-Phenylethanol
-
-
2425-28-7
2-Bromo-1-phenylethanol
-
-
450-94-2
2-fluoro-1-phenylethanol
-
-
1528-01-4
methyltributyltin
| Conditions | Yield |
|---|---|
|
In
tetrahydrofuran;
at -98 ℃;
Inert atmosphere;
|
15 %Spectr.
20 %Spectr. 55 %Spectr. |
2425-28-7 Upstream products
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100-42-5
styrene
-
96-09-3
styrene oxide
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60-29-7
diethyl ether
-
24442-57-7
1,2-dibromoethyl acetate
2425-28-7 Downstream products
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6318-99-6
1-(2-hydroxy-2-phenylethyl)pyridinium bromide
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6689-06-1
1-(2-hydroxy-2-phenylethyl)-2-methylpyridinium bromide
-
14272-71-0
3-(β-hydroxy-phenethyl)-4-methyl-thiazolium; bromide
-
7155-43-3
2-(β-hydroxy-phenethyl)-isoquinolinium; iodide
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