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Reputable factory supply (E)-1-benzhydryl-4-cinnamylpiperazine 16699-20-0 in stock with high standard
- Molecular Formula: C26H28N2
- Molecular Weight: 368.522
- Vapor Pressure: 1.74E-10mmHg at 25°C
- Boiling Point: 509.2°Cat760mmHg
- Flash Point: 229.8°C
- PSA: 6.48000
- Density: 1.093g/cm3
- LogP: 4.98280
(E)-1-benzhydryl-4-cinnamylpiperazine(Cas 16699-20-0) Usage
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General Description |
(E)-1-benzhydryl-4-cinnamylpiperazine is a chemical compound that belongs to the class of piperazines, which are organic compounds that contain a six-membered ring with two nitrogen atoms and four carbon atoms. This specific compound is a piperazine derivative that contains a benzhydryl group and a cinnamyl group, with the piperazine ring being in a trans configuration. It has been studied for its potential pharmacological properties, including its activity as a serotonin reuptake inhibitor and its potential as an antipsychotic agent. (E)-1-benzhydryl-4-cinnamylpiperazine has also been investigated for its potential use in the treatment of various neurological and psychiatric disorders. The compound's chemical structure and properties make it an interesting target for medicinal chemistry research. |
InChI:InChI=1/C26H28N2/c1-4-11-23(12-5-1)13-10-18-27-19-21-28(22-20-27)26(24-14-6-2-7-15-24)25-16-8-3-9-17-25/h1-17,26H,18-22H2/b13-10-
16699-20-0 Relevant articles
Iron-catalyzed synthesis of cinnarizine
Shakhmaev,Sunagatullina, A. Sh.,Zorin
, p. 95 - 97 (2015)
Cinnarizine was synthesized in a high yi...
Allyl coupling reaction method and application thereof
-
Paragraph 0304-0308, (2021/08/25)
The invention discloses a novel allyl co...
Oxidative Rearrangement of MIDA (N-Methyliminodiacetic Acid) Boronates: Mechanistic Insights and Synthetic Applications
Kaldas, Sherif J.,Tien, Chieh-Hung,Gomes, Gabriel Dos Passos,Meyer, Stephanie,Sirvinskas, Martynas,Foy, Hayden,Dudding, Travis,Yudin, Andrei K.
supporting information, p. 324 - 328 (2021/01/26)
Herein we report that coordinative hemil...
Scalable preparation of stable and reusable silica supported palladium nanoparticles as catalysts for N-alkylation of amines with alcohols
Alshammari, Ahmad S.,Natte, Kishore,Kalevaru, Narayana V.,Bagabas, Abdulaziz,Jagadeesh, Rajenahally V.
, p. 141 - 149 (2020/01/06)
The development of nanoparticles-based h...
Palladium-Based Hydroamination Catalysts Employing Sterically Demanding 3-Iminophosphines: Branched Kinetic Products by Prevention of Allylamine Isomerization
Thakuri, Rajendr S.,Schmidt, Joseph A. R.
, p. 1917 - 1927 (2019/05/21)
A new allylpalladium triflate catalyst w...
16699-20-0 Process route
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-
4393-06-0
1-Phenyl-2-propen-1-ol
-
-
841-77-0
diphenylmethylpiperazine
-
-
298-57-7,16699-20-0
cinnarizine
| Conditions | Yield |
|---|---|
|
With
Pd(xantphos)(MeCN)2(OTf)2;
In
isopropyl alcohol;
at 20 ℃;
for 12h;
Inert atmosphere;
|
95%
|
-
-
104-54-1
3-Phenylpropenol
-
-
841-77-0
diphenylmethylpiperazine
-
-
298-57-7,16699-20-0
cinnarizine
| Conditions | Yield |
|---|---|
|
In
o-xylene;
at 150 ℃;
for 30h;
Inert atmosphere;
Sealed tube;
|
90%
|
16699-20-0 Upstream products
-
104-54-1
3-Phenylpropenol
-
841-77-0
diphenylmethylpiperazine
-
104-55-2
3-phenyl-propenal
-
2327-99-3
1-phenylpropadiene
16699-20-0 Downstream products
-
1439890-20-6
C36 H39 Cl3 N4 O4 S
-
1439890-25-1
C36 H39 Cl3 N4 O4 S
-
7002-58-6
(Z)-1-(diphenylmethyl)-4-cinnamylpiperazine dihydrochloride
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48218-32-2
1-(diphenylmethyl)-4-(3-phenylpropyl)piperazine
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