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1,2-Dichloro-4-(chloromethyl)benzene

  • CAS：102-47-6
  • purity：99%
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Manufacturer supply high quality 1,2-Dichloro-4-(chloromethyl)benzene 102-47-6 with GMP standards

  • Molecular Formula: C7H5Cl3
  • Molecular Weight: 195.476
  • Appearance/Colour: Clear to yellowish liquid 
  • Vapor Pressure: 0.057mmHg at 25°C 
  • Melting Point: -3 °C 
  • Refractive Index: n20/D 1.577(lit.)  
  • Boiling Point: 241 °C at 760 mmHg 
  • Flash Point: 160.2 °C 
  • PSA： 0.00000 
  • Density: 1.386 g/cm3 
  • LogP: 3.73220 

1,2-Dichloro-4-(chloromethyl)benzene(Cas 102-47-6) Usage

InChI:InChI=1/C7H5Cl3/c8-4-5-1-2-6(9)7(10)3-5/h1-3H,4H2

102-47-6 Relevant articles

Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-β-lactamase inhibitors

Yan, Yu-Hang,Li, Wenfang,Chen, Wei,Li, Chao,Zhu, Kai-Rong,Deng, Ji,Dai, Qing-Qing,Yang, Ling-Ling,Wang, Zhenling,Li, Guo-Bo

, (2021/11/17)

Production of metallo-β-lactamases (MBLs...

N-(Substituted sulfonyl)benzamide derivative and preparation method and pharmaceutical application thereof

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Paragraph 0677; 0679-0683, (2019/04/17)

The invention relates to an N-(substitut...

NOVEL DXR INHIBITORS FOR ANTIMICROBIAL THERAPY

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Page/Page column 89-90, (2011/05/05)

The present invention generally concerns...

Synthesis and antiparasitic and antitumor activity of 2,4-diamino-6- (arylmethyl)-5,6,7,8-tetrahydroquinazoline analogues of piritrexim

Rosowsky, Andre,Papoulis, Andrew T.,Forsch, Ronald A.,Queener, Sherry F.

, p. 1007 - 1017 (2007/10/03)

Nineteen previously undescribed 2,4-diam...

102-47-6 Process route

3,4-dichlorobenzyl alcohol
1805-32-9

3,4-dichlorobenzyl alcohol

3,4-Dichlorophenylmethyl chloride
102-47-6

3,4-Dichlorophenylmethyl chloride

Conditions
Conditions Yield
With thionyl chloride; In toluene; for 0.0833333h; Ambient temperature;
With thionyl chloride; In dichloromethane; at 0 - 20 ℃; for 3h;
With thionyl chloride; at 60 ℃; for 2h;
With thionyl chloride; In dichloromethane; at 20 ℃;
3,4-dichlorobenzaldehyde
6287-38-3

3,4-dichlorobenzaldehyde

3,4-Dichlorophenylmethyl chloride
102-47-6

3,4-Dichlorophenylmethyl chloride

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: NaBH4 / methanol / Ambient temperature
2: SOCl2 / toluene / 0.08 h / Ambient temperature
With sodium tetrahydroborate; thionyl chloride; In methanol; toluene;
Multi-step reaction with 2 steps
1: sodium tetrahydroborate; methanol / 1 h / 0 - 20 °C
2: thionyl chloride / dichloromethane / 3 h / 0 - 20 °C
With methanol; sodium tetrahydroborate; thionyl chloride; In dichloromethane;

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    1-(3,4-dichloro-benzyl)-piperazine; dihydrochloride

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