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2,6-Difluorophenol

  • CAS：28177-48-2
  • purity：99%
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Manufacturer supply 2,6-Difluorophenol 28177-48-2 with sufficient stock and high standard

  • Molecular Formula: C6H4F2O
  • Molecular Weight: 130.094
  • Appearance/Colour: white crystal 
  • Vapor Pressure: 2.11mmHg at 25°C 
  • Melting Point: 38-42 °C 
  • Refractive Index: 1.495 
  • Boiling Point: 157.7 °C at 760 mmHg 
  • PKA: 7.45±0.10(Predicted) 
  • Flash Point: 58 °C 
  • PSA： 20.23000 
  • Density: 1.351 g/cm3 
  • LogP: 1.67040 

2,6-Difluorophenol(Cas 28177-48-2) Usage

General Description

2,6-Difluorophenol is a fluorinated phenol derivative used as a key starting material in the synthesis of fluorine-substituted hexabenzocoronene (HBC) compounds. Its electron-withdrawing fluorine groups help balance the electron-donating effects of alkoxy substituents, improving the stability and electronic properties of the resulting HBC derivatives. These modified HBCs exhibit columnar self-assembly and charge-carrier mobility comparable to nonfluorinated analogs, making them promising for optoelectronic applications.

InChI:InChI=1/C6H4F2O/c7-4-2-1-3-5(8)6(4)9/h1-3,9H

28177-48-2 Relevant articles

Synthesis method of fluorine-containing phenol structure compound

-

Paragraph 0023-0024, (2021/03/13)

The invention discloses a synthesis meth...

A practical method for preparation of phenols from arylboronic acids catalyzed by iodopovidone in aqueous medium

Dong, Bin,Ke, Yanxiong,Lu, Guangying,Ren, Jiangmeng,Ren, Yaoyao,Zeng, Bu-Bing,Zhou, Bin

, (2019/09/06)

A novel and efficient strategy for the i...

A aqueous phase preparation 2, 6 - [...] method

-

, (2019/03/28)

The invention relates to a green prepara...

Method for preparing 2,6-difluoroindophenol acetate

-

, (2019/03/28)

The invention relates to a novel synthet...

28177-48-2 Process route

phenol
108-95-2,27073-41-2

phenol

4-Fluorophenol
371-41-5

4-Fluorophenol

2-fluorophenol
367-12-4

2-fluorophenol

2,6-difluorophenol
28177-48-2

2,6-difluorophenol

Conditions
Conditions Yield
With fluorine; at 40 - 50 ℃; for 8h; Reagent/catalyst; Inert atmosphere; Large scale;
phenol
108-95-2,27073-41-2

phenol

4-Fluorophenol
371-41-5

4-Fluorophenol

2-fluorophenol
367-12-4

2-fluorophenol

2,4-difluorophenol
367-27-1

2,4-difluorophenol

2,6-difluorophenol
28177-48-2

2,6-difluorophenol

Conditions
Conditions Yield
With fluorine; at 40 - 50 ℃; for 8h; Inert atmosphere; Large scale;

28177-48-2 Upstream products

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    437-82-1

    1,3-difluoro-2-methoxybenzene

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    1,3-Difluorobenzene

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    162101-25-9

    2,6-difluorophenylboronic acid

  • 820220-75-5
    820220-75-5

    2,6-difluorophenyl phenyl sulfate

28177-48-2 Downstream products

  • 363-45-1
    363-45-1

    2,6-difluorophenoxyacetic acid

  • 437-82-1
    437-82-1

    1,3-difluoro-2-methoxybenzene

  • 117923-74-7
    117923-74-7

    C6 (13) CH6 F2 O

  • 118276-06-5
    118276-06-5

    3,5-difluoro-4-hydroxybenzaldehyde

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