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Quality products?make an important contribution to long-term revenue and profitability. Reputable factory supply Folinic acid 58-05-9 in bulk at low price
1.What is the Folinic acid ?
Folinic Acid is used in combination with 5-fluorouracil in the treatment of colorectal cancers. It also functions as a useful antidotal therapy medication for decreasing the toxic effect of methotrexate overdosing.
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6035-45-6
Leucovorin Calcium
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58-05-9
folinic acid
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
water;
at 6 - 10 ℃;
for 4h;
pH=2.8 - 3.2;
|
99.4 % ee
|
|
With
acetic acid;
In
water;
at 2 - 12 ℃;
pH=2.5 - 3.5;
|
-
-
58-05-9
folinic acid
| Conditions | Yield |
|---|---|
|
|
3.0 g (65%)
|
|
|
|
|
|
2.What is the CAS number for Folinic acid ?
The CAS number of Folinic acid is 58-05-9.
More information of Folinic acid 58-05-9 are:
|
CAS?Number |
58-05-9 |
|
Density |
1.68 g/cm3 |
|
Melting Point |
245ºC (decomp) |
|
Boiling Point |
573.92°C (rough estimate) |
|
Refractive Index |
1.6800 (estimate) |
|
PSA |
219.84000 |
|
LogP |
1.15290 |
|
Pka |
3.1, 4.8, 10.4(at 25℃) |
3.What are another words for Folinic acid ?
Synonyms?for?Folinic acid 58-05-9:Glutamicacid, N-[p-[[(2-amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-,L- (8CI);L-Glutamic acid,N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-(9CI);(6R,S)-5-Formyltetrahydrofolate;5-Formyl-5,6,7,8-tetrahydrofolic acid;5-Formyltetrahydrofolic acid;5-Formyltetrahydropteroylglutamic acid;CF;Folinic acid;Folinic acid-SF;Leucal;Leucoverin;Leucovorin;Levoleucovorin;N5-Formyl-5,6,7,8-tetrahydrofolic acid;N5-Formyltetrahydrofolic acid;Welcovorin;l-Leucovorin;
4.What is the molecular formula of Folinic acid?
The chemical formula of ?Folinic acid is?C20H23N7O7 which containing 20 Carbon atoms,23 Hydrogen atoms,7 Nitrogen atoms and 7 Oxygen atoms,and the molecular weight of??Folinic acid?is 473.445.
5.What is Folinic acid (58-05-9) used for?
Folinic acid, chemical name N-[4-[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridyl) Methyl]amino]benzoyl-L-glutamic acid has been widely used in cancer combined chemotherapy. Folinic acid enters the human body through the ingestion and absorption pathway of folate. Folinic acid (calcium folinate) is a special form of reduced folic acid (folate).
InChI:InChI=1/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12-,13-/m0/s1
Relevant articles related to Folinic acid:
|
Article |
Source |
|
THERAPEUTIC FOR HEPATIC CANCER |
- , (2011/02/18) |
|
METHOD FOR THE PRODUCTION OF CRYSTALLINE (6RS)-N(5)-FORMYL-5,6,7,8-TETRAHYDROFOLIC ACID |
- Page/Page column 9-11, (2008/06/13) |
6.Buy Folinic acid with the best price .
wuxi huabin bio-tech Co.,Ltd is a quality supplier of Folinic acid. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Folinic acid 58-05-9.
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