Organic Chemicals

Folinic acid

  • CAS:58-05-9
  • purity:99%
Inquiry

Quality products?make an important contribution to long-term revenue and profitability. Reputable factory supply Folinic acid 58-05-9 in bulk at low price

1.What is the Folinic acid ?

Folinic Acid is used in combination with 5-fluorouracil in the treatment of colorectal cancers. It also functions as a useful antidotal therapy medication for decreasing the toxic effect of methotrexate overdosing.

Leucovorin Calcium
6035-45-6

Leucovorin Calcium

folinic acid
58-05-9

folinic acid

Conditions
Conditions Yield
With hydrogenchloride; In water; at 6 - 10 ℃; for 4h; pH=2.8 - 3.2;
99.4 % ee
With acetic acid; In water; at 2 - 12 ℃; pH=2.5 - 3.5;
folinic acid
58-05-9

folinic acid

Conditions
Conditions Yield
3.0 g (65%)

2.What is the CAS number for Folinic acid ?

The CAS number of Folinic acid is 58-05-9.

More information of Folinic acid 58-05-9 are:

CAS?Number

58-05-9

Density

1.68 g/cm3

Melting Point

245ºC (decomp)

Boiling Point

573.92°C (rough estimate)

Refractive Index

1.6800 (estimate)

PSA

219.84000

LogP

1.15290

Pka

3.1, 4.8, 10.4(at 25℃)

3.What are another words for Folinic acid ?

Synonyms?for?Folinic acid 58-05-9:Glutamicacid, N-[p-[[(2-amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-,L- (8CI);L-Glutamic acid,N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-(9CI);(6R,S)-5-Formyltetrahydrofolate;5-Formyl-5,6,7,8-tetrahydrofolic acid;5-Formyltetrahydrofolic acid;5-Formyltetrahydropteroylglutamic acid;CF;Folinic acid;Folinic acid-SF;Leucal;Leucoverin;Leucovorin;Levoleucovorin;N5-Formyl-5,6,7,8-tetrahydrofolic acid;N5-Formyltetrahydrofolic acid;Welcovorin;l-Leucovorin;

4.What is the molecular formula of Folinic acid?

The chemical formula of ?Folinic acid is?C20H23N7O7 which containing 20 Carbon atoms,23 Hydrogen atoms,7 Nitrogen atoms and 7 Oxygen atoms,and the molecular weight of??Folinic acid?is 473.445.

5.What is Folinic acid (58-05-9) used for?

Folinic acid, chemical name N-[4-[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridyl) Methyl]amino]benzoyl-L-glutamic acid has been widely used in cancer combined chemotherapy. Folinic acid enters the human body through the ingestion and absorption pathway of folate. Folinic acid (calcium folinate) is a special form of reduced folic acid (folate).

InChI:InChI=1/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12-,13-/m0/s1

Relevant articles related to Folinic acid:

Article

Source

THERAPEUTIC FOR HEPATIC CANCER

-

, (2011/02/18)

METHOD FOR THE PRODUCTION OF CRYSTALLINE (6RS)-N(5)-FORMYL-5,6,7,8-TETRAHYDROFOLIC ACID

-

Page/Page column 9-11, (2008/06/13)

6.Buy Folinic acid with the best price .

wuxi huabin bio-tech Co.,Ltd is a quality supplier of Folinic acid. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Folinic acid 58-05-9.

Shopping Cart

Clear Inquiry